Grey's Anatomy Season 10 Spoilers: Callie's Parents, Shane's Guilt, And An Arizona-Centric Episode?

"Grey's Anatomy" season 10 is more dramatic than ever, and more spoilers are arriving about Callie, Arizona, and Shane.

For fans who are dying about the latest development regarding Callie and Arizona, it seems both characters will receive major screentime in the future, and with unlikely partners too!

For Callie, it seems the actress has been shooting on location with not one, but two guest stars, and the major consensus believes that this spoiler is hinting at none other than Callie's parents.

We haven't seen Callie's parents on "Grey's Anatomy" since Callie and Arizona's wedding, so it'll be interesting to see how Carlos and Lucia Torres are now that the couple is on the fritz.

As for Arizona, fans are getting jittery with spoilers hinting at a potential pairing with Leah.

"At a certain point, when you're being cast as the villain, then the villain realizes that even though they don't feel very villainous, they're going to at least need some friends and people to relate to on some level. The attention and the possibility make her feel something that's not bad," says Jessica Capshaw to TVGuide.

"It's not like she's running into a relationship and being like, 'Oh, this thing with Callie is over, so I'm going to start this new big thing.' It's just very human. She's felt very bad for quite a while, and this is something that offers her a little relief from that."

And reportedly, the November 14 episode will feature Arizona heavily.

Lastly, "Grey's Anatomy" season 10 hasn't dealt with Shane's guilt over Heather's death since the premiere, but spoilers confirm that the intern will continue to explore these feelings in the very near future.

"We'll have to see Shane balance that sort of personal trauma with how he does his job and falls in line at the hospital. It's going to be pretty cool, pretty interesting," says actor Gaius Charles according to TVLine.