Amanda Knox, the American exchange student who served four years in an Italian prison for killing another student, could be retried if prosecutors get their wish.

On Monday Italy's Supreme Court will decide if the Amanda Knox, who was acquitted on appeal in 2011, can be forced to submit to a retrial, according to CNN.

"The appeal of Amanda's acquittal by the prosecution was not unexpected as they had indicated from the day of the verdict that they would appeal," reads a family statement from February of 2012.

In 2007, Amanda Knox, then 20, moved to Perugia, Italy, to attend the University For Foreigners of Perugia. She shared a room with another student studying abroad, 21-year-old Meredith Kercher from England.

In November of that year Kercher's semi-naked corpse was found at the Perugia apartment she shared with Knox, who became a prime suspect.

Police arrested Knox and her then-boyfriend Raffaele Sollecito. After serving four-year sentences for the murder, their conviction was overturned in late 2011.

The judge wrote that the jury cleared the accused murderers on account of insufficient evidence.

Perugia prosecutor Giovanni Galati told the Italian news agency ANSA that the Amanda Knox case should be retried because justice was not served.

"We are still convinced that they are the co-authors of Meredith's homicide," Galati said.

Rudy Guede, a drifter from the Ivory Coast, was also convicted in Kercher's killing. He admitted having sex with Kercher but denied the murder.

In the 18 months since her murder conviction was overturned, Knox returned to her hometown of Seattle, Wash. where she is currently attending the University of Washington.

She wrote a book on the subject called "Waiting To Be Heard" that will be out next month.

Raffaele Sollecito's father Francesco Sollecito told CNN last year that he was unhappy about the prosecution's decision to appeal.

"[The family is] not happy about the decision," Francesco said. "My son is trying to get back to normal life...we can do very little in this situation, but as Italian citizens, they would have to accept the court's decision. We hope that the high court will finally put the words 'the end' to this story."

If Italy's Supreme Court rules that the Amanda Knox case can be retried and she and her boyfriend refuse to return to Italy for the trial, the court could request their expedition from the U.S.